Receptor for both mineralocorticoids(MC) such as aldosterone and glucocorticoids(GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements(MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Host
Rabbit
Immunogen
nuclear receptor subfamily 3, group C, member 2
Isotype
IgG
Molecular Weight
107 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
MCR, Mineralocorticoid receptor, MLR, MR, NR3C2
Uniprot
P08235
Gene Id
4306
Research Area
Cardiovascular, Metabolism, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)