Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod-and cone-specific genes, including rhodopsin, M-and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M-and S-cone opsin expression.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
Host
Rabbit
Immunogen
nuclear receptor subfamily 2, group E, member 3
Isotype
IgG
Molecular Weight
43-45 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ESCS, NR2E3, PNR, rd7, RNR, RP37
Antigen
NR2E3
Uniprot
Q9Y5X4
Gene Id
10002
Research Area
Developmental biology, Signal Transduction, Metabolism, Stem Cells, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)