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Home / Primary Antibodies / Polyclonal Antibodies

NF2 antibody

SKU : BHA10805677

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Mfr.No.	FNab05685
Alternative Names	SCH
Background	Probable regulator of the Hippo/SWH(Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH(Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
Host	Rabbit
Immunogen	neurofibromin 2(merlin)
Isotype	IgG
Molecular Weight	66-70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	SCH,ACN, BANF, Merlin, Neurofibromin 2, neurofibromin 2(merlin), NF2

Uniprot	P35240
Gene Id	4771
Research Area	Stem Cells

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

Manual	FNab05685.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805677	FNab05685	100ug	$240		Add to Cart

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