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Home / Primary Antibodies / Monoclonal Antibodies

NENF antibody

SKU : BHA10805653

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Mfr.No.	FNab05661
Alternative Names	CIR2 ; SPUF
Background	Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190).
Categories	Primary Antibodies
Clonality	monoclonal
Description	Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190).
Host	Mouse
Immunogen	neuron derived neurotrophic factor
Isotype	IgG2a
Molecular Weight	18 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	CIR2, NENF, NEUDESIN, SCIRP10, SPUF, SPUF protein

Uniprot	Q9UMX5
Gene Id	29937
Clone No	7C8
Research Area	Neuroscience

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500

Manual	FNab05661.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805653	FNab05661	100ug	$280		Add to Cart

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