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Home / Primary Antibodies / Polyclonal Antibodies

NEDD8 antibody

SKU : BHA10805639

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Mfr.No.	FNab05647
Background	NEDD8 (neural precursor cell expressed, developmentally down-regulated 8) is a protein-coding gene. Diseases associated with NEDD8 include glomuvenous malformation. GO annotations related to this gene include ubiquitin protein ligase binding.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C- APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Host	Rabbit
Immunogen	neural precursor cell expressed, developmentally down-regulated 8
Isotype	IgG
Molecular Weight	12 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	NEDD-8

Uniprot	Q15843
Gene Id	4738
Research Area	Epigenetics, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab05647.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805639	FNab05647	100ug	$240		Add to Cart

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