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Home / Primary Antibodies / Polyclonal Antibodies

NCL antibody

SKU : BHA10805579

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Mfr.No.	FNab05587
Background	Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
Host	Rabbit
Immunogen	nucleolin
Isotype	IgG
Molecular Weight	110 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	C23

Uniprot	P19338
Gene Id	4691
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab05587.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805579	FNab05587	100ug	$260		Add to Cart

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