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Home / Primary Antibodies / Monoclonal Antibodies

N-cadherin antibody

SKU : BHA10805563

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Mfr.No.	FNab05571
Background	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	cadherin 2, type 1, N-cadherin(neuronal)
Isotype	IgG2a
Molecular Weight	130 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin

Uniprot	P19022
Gene Id	1000
Clone No	1G1
Research Area	Signal Transduction, Cardiovascular, Immunology, Stem Cells, Neuroscience

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:1000-1:10000; IHC: 1:20-1:200

Manual	FNab05571.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805563	FNab05571	100ug	$260		Add to Cart

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