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Home / Primary Antibodies / Polyclonal Antibodies

MYLIP antibody

SKU : BHA10805484

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Mfr.No.	FNab05492
Alternative Names	BZF1 ; IDOL
Background	The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol- dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
Host	Rabbit
Immunogen	myosin regulatory light chain interacting protein
Isotype	IgG
Molecular Weight	50 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BZF1, IDOL

Uniprot	Q8WY64
Gene Id	29116
Research Area	Epigenetics, Developmental biology, Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab05492.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805484	FNab05492	100ug	$260		Add to Cart

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