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Home / Primary Antibodies / Polyclonal Antibodies

Myelin basic protein antibody

SKU : BHA10805457

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Mfr.No.	FNab05465
Background	The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	myelin basic protein
Isotype	IgG
Molecular Weight	14-18 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	MBP, Myelin A1 protein, Myelin basic protein

Uniprot	P02686
Gene Id	4155
Research Area	Stem Cells, Immunology, Cancer, Neuroscience
Weight	22kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:1000-1:10000
IHC	1:50-1:500

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Reference	Journal: Acs Nano Title: Flexible and Highly Biocompatible Nanober- Based Electrodes for NeuralS urface Interfacing

Manual	FNab05465.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805457	FNab05465	100ug	$240		Add to Cart

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