Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Host
Rabbit
Immunogen
melanoma associated antigen(mutated) 1
Isotype
IgG
Molecular Weight
70-80 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
EXPAND1
Uniprot
Q2TAK8
Gene Id
84939
Research Area
Cell Division and Proliferation, Cancer, Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)