May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor(HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Categories
Primary Antibodies
Clonality
polyclonal
Description
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Host
Rabbit
Immunogen
mucin 20, cell surface associated
Isotype
IgG
Molecular Weight
70-75kd
Reactivity
Human
Regulatory
RUO
Synonyms
KIAA1359
Uniprot
Q8N307
Gene Id
200958
Research Area
Cancer, Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)