Modulator of melanocortin receptors(MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin(ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.
Host
Rabbit
Immunogen
melanocortin 2 receptor accessory protein
Isotype
IgG
Molecular Weight
12 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
C21orf61, FALP
Uniprot
Q8TCY5
Gene Id
56246
Research Area
Signal Transduction, Immunology, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)