This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.
Host
Rabbit
Immunogen
renal tumor antigen
Isotype
IgG
Molecular Weight
40 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
RAGE, RAGE1
Uniprot
Q9UQ07
Gene Id
5891
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)