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Home / Antibodies

MMP2 Antibody (RQ5213)

SKU : BHA17109929

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NSJ Bioreagents

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Mfr.No.	RQ5213
Clonality	Monoclonal
Description	The MMP2 gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human MMP2 was used as the immunogen for the MMP2 antibody.
Isotype	IgG
Predicted Reactivity	Human, Rat
Reactivity	Human, Rat
Recombinant	No

Uniprot	P08253
Clone No	BBA-13

Format	Purified
Purification	Affinity purified
Storage	Store the MMP2 antibody at -20°C.

Applications	IHC-P, WB
Dilution	Weste blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:50-1:200

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109929	RQ5213	100ul	$419		Add to Cart

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