Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein(comp), during development, haemostasis and pathological conditions(arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Host
Rabbit
Immunogen
matrix metallopeptidase 19
Isotype
IgG
Molecular Weight
57-60 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
MMP18, RASI
Uniprot
Q99542
Gene Id
4327
Research Area
Developmental biology, Cardiovascular, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)