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Home / Primary Antibodies / Polyclonal Antibodies

MLXIP antibody

SKU : BHA10805215

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Mfr.No.	FNab05223
Alternative Names	BHLHE36 ; KIAA0867 ; MIR ; MONDOA
Background	Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Host	Rabbit
Immunogen	MLX interacting protein
Isotype	IgG
Molecular Weight	130 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BHLHE36, KIAA0867, MIR, MONDOA

Uniprot	Q9HAP2
Gene Id	22877
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

Manual	FNab05223.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805215	FNab05223	100ug	$240		Add to Cart

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