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Home / Primary Antibodies / Polyclonal Antibodies

MITF antibody

SKU : BHA10805190

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Mfr.No.	FNab05198
Alternative Names	BHLHE32
Background	Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Host	Rabbit
Immunogen	microphthalmia-associated transcription factor
Isotype	IgG
Molecular Weight	60-65kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	bHLHe32, MI, MITF, WS2A

Uniprot	O75030
Gene Id	4286
Research Area	Epigenetics, Developmental biology, Metabolism, Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, FC, IP
Description	ELISA ; WB ; FC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:2000

Manual	FNab05198.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805190	FNab05198	100ug	$240		Add to Cart

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