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Home / Primary Antibodies / Polyclonal Antibodies

MIP antibody

SKU : BHA10805185

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Mfr.No.	FNab05193
Alternative Names	AQP0
Background	Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (PubMed:24120416).
Host	Rabbit
Immunogen	major intrinsic protein of lens fiber
Isotype	IgG
Molecular Weight	28 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AQP0

Uniprot	P30301
Gene Id	4284
Research Area	Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:1000; IHC: 1:100 - 1:200

Manual	FNab05193.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805185	FNab05193	100ug	$260		Add to Cart

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