Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Host
Rabbit
Immunogen
MHC class I polypeptide-related sequence B
Isotype
IgG
Molecular Weight
43 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
MICB, PERB11.2, MHC class I polypeptide-related sequence B
Uniprot
Q29980
Gene Id
4277
Research Area
Epigenetics, Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)