Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Clonality
polyclonal
Host
Rabbit
Immunogen
MHC class I polypeptide-related sequence B
Immunogen Region
MHC class I polypeptide-related sequence B
Isotype
IgG
Molecular Weight
40-60 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Synonyms
MICB, PERB11.2, MHC class I polypeptide-related sequence B
Uniprot
Q29980
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10743.pdf" target="_blank">Data Sheet</ a>