E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).
Host
Rabbit
Immunogen
mindbomb homolog 2(Drosophila)
Isotype
IgG
Molecular Weight
74 kDa, 82 kDa, 110 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
SKD, ZZANK1
Uniprot
Q96AX9
Gene Id
142678
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)