Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors(LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
Host
Rabbit
Immunogen
mesoderm development candidate 2
Isotype
IgG
Molecular Weight
26-28 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
KIAA0081, MESD
Uniprot
Q14696
Gene Id
23184
Research Area
Developmental biology, Stem Cells
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)