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Home / Primary Antibodies / Polyclonal Antibodies

MEF2C-Specific antibody

SKU : BHA10805099

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Mfr.No.	FNab05107
Background	MEF2C belongs to the MEF2 family. It is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. This protein is required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. It may also be involved in neurogenesis and in the development of cortical architecture. The immunogen used is peptide from the specific sequecne of MEF2C transcript variant 1 match to transcript variant 5. The antibody can recognize the transcript variant 1, transcript variant 2 and transcript variant 3 of MEF2C.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	myocyte enhancer factor 2C
Isotype	IgG
Molecular Weight	51 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	Q06413
Research Area	Developmental biology, Metabolism, Cardiovascular, Immunology, Stem Cells, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	WB: 1:500-1:1000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805099	FNab05107	100ug	$240		Add to Cart

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