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Home / Primary Antibodies / Polyclonal Antibodies

MCM2 antibody

SKU : BHA10805048

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Mfr.No.	FNab05056
Alternative Names	BM28 ; CCNL1 ; CDCL1 ; KIAA0030
Background	Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
Host	Rabbit
Immunogen	minichromosome maintenance complex component 2
Isotype	IgG
Molecular Weight	116-125 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BM28, CCNL1, CDCL1, KIAA0030

Uniprot	P49736
Gene Id	4171
Research Area	Epigenetics, Cancer, Immunology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805048	FNab05056	100ug	$240		Add to Cart

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