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Home / Primary Antibodies / Polyclonal Antibodies

MBL2 antibody

SKU : BHA10805032

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Mfr.No.	FNab05040
Alternative Names	COLEC1 ; Collectin1 ; HSMBPC ; Mannanbindingprotein ; Mannosebindinglectin ; MannosebindingproteinC ; MBL ; MBL2 ; MBP ; MBPC ; MBP1
Background	This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Host	Rabbit
Immunogen	mannose-binding lectin (protein C) 2, soluble (opsonic defect)
Isotype	IgG
Molecular Weight	30 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	COLEC1, Collectin 1, HSMBPC, Mannan binding protein, Mannose binding lectin, Mannose binding protein C, MBL, MBL2, MBP, MBP C, MBP1

Uniprot	P11226
Gene Id	4153
Research Area	Immunology
Weight	30kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab05040.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805032	FNab05040	100ug	$280		Add to Cart

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