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Home / Primary Antibodies / Polyclonal Antibodies

MASP1 antibody

SKU : BHA10805013

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Mfr.No.	FNab05021
Alternative Names	CRARF ; CRARF1 ; PRSS5
Background	Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin(MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Host	Rabbit
Immunogen	mannan-binding lectin serine peptidase 1(C4/C2 activating component of Ra-reactive factor)
Isotype	IgG
Molecular Weight	40-70 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	CRARF, CRARF1, PRSS5

Uniprot	P48740
Gene Id	5648
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805013	FNab05021	100ug	$280		Add to Cart

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