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Home / Primary Antibodies / Polyclonal Antibodies

MAPKBP1 antibody

SKU : BHA10804992

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Mfr.No.	FNab05000
Alternative Names	JNKBP1 ; KIAA0596
Background	MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-beta-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFkappaB (nuclear factor kappa-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in JNK signaling pathway.
Host	Rabbit
Immunogen	mitogen-activated protein kinase binding protein 1
Isotype	IgG
Molecular Weight	165 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	JNKBP1, KIAA0596

Uniprot	O60336
Gene Id	23005
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:200 - 1:500; IHC: 1:50 - 1:100

Manual	FNab05000.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804992	FNab05000	100ug	$240		Add to Cart

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