Atypical MAPK protein. Phosphorylates microtubule-associated protein 2(MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in tu phosphorylates ERK4/MAPK4. May promote entry in the cell cycle(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in tu phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
Host
Rabbit
Immunogen
mitogen-activated protein kinase 4
Isotype
IgG
Molecular Weight
68 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ERK4, PRKM4
Antigen
MAPK4
Uniprot
P31152
Gene Id
5596
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)