Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Host
Rabbit
Immunogen
mitogen-activated protein kinase kinase kinase kinase 4
Isotype
IgG
Molecular Weight
130-160 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HGK, KIAA0687, NIK
Uniprot
O95819
Gene Id
9448
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)