Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Host
Rabbit
Immunogen
mitogen-activated protein kinase kinase kinase kinase 4
Isotype
IgG
Molecular Weight
130-160 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HGK, KIAA0687, NIK
Antigen
MAP4K4
Uniprot
O95819
Gene Id
9448
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)