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Home / Primary Antibodies / Polyclonal Antibodies

MAGEA1 antibody

SKU : BHA10804925

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Mfr.No.	FNab04933
Alternative Names	MAGE1 ; MAGE1A
Background	This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Categories	Primary Antibodies
Clonality	polyclonal
Description	May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Host	Rabbit
Immunogen	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
Isotype	IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	MAGE1, MAGE1A

Uniprot	P43355
Gene Id	4100
Research Area	Developmental biology, Cancer

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab04933.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804925	FNab04933	100ug	$280		Add to Cart

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