Binds bacterial lipopolysaccharide(LPS)(PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide(LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria(PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B(PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS(PubMed:10359581).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram- positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581).
Host
Rabbit
Immunogen
lymphocyte antigen 96
Isotype
IgG
Molecular Weight
20 kDa, 30 kDa, 35 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ESOP1, MD2
Uniprot
Q9Y6Y9
Gene Id
23643
Research Area
Signal Transduction, Metabolism, Cancer, Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)