Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing(By similarity). Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing (By similarity). Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA.
Host
Rabbit
Immunogen
LSM11, U7 small nuclear RNA associated
Isotype
IgG
Molecular Weight
45-50 kDa
Reactivity
Human
Regulatory
RUO
Antigen
LSM11
Uniprot
P83369
Gene Id
134353
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)