Possesses both acyltransferase and acetyltransferase activities(PubMed:16864775, PubMed:21498505). Activity is calcium-independent(By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine(LPC) into phosphatidylcholine(PC)(PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively(PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology(PubMed:16864775). Involved in the regulation of lipid droplet number and size(PubMed:25491198).
Categories
Primary Antibodies
Clonality
monoclonal
Description
Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505). Activity is calcium-independent (By similarity). Mediates the conversion of 1- acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16864775). Involved in the regulation of lipid droplet number and size (PubMed:25491198).
Host
Mouse
Immunogen
lysophosphatidylcholine acyltransferase 1
Isotype
IgG2a
Molecular Weight
55 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
AYTL2, PFAAP3
Uniprot
Q8NF37
Gene Id
79888
Clone No
7E4
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)