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Home / Primary Antibodies / Polyclonal Antibodies

LOXL1 antibody

SKU : BHA10809964

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Mfr.No.	FNab09975
Background	This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.
Clonality	polyclonal
Host	Rabbit
Immunogen	lysyl oxidase-like 1
Immunogen Region	lysyl oXidase-like 1
Isotype	IgG
Molecular Weight	70kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500 - 1:2000
Synonyms	LOL, LOXL, LOXL1, Lysyl oxidase homolog 1, lysyl oxidase like 1, Lysyl oxidase like protein 1

Uniprot	Q08397
Gene Id	4016
Research Area	Cancer, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09975.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809964	FNab09975	100ug	$260		Add to Cart

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