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Home / Primary Antibodies / Monoclonal Antibodies

LONP1 antibody

SKU : BHA10804813

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Mfr.No.	FNab04821
Alternative Names	PRSS15
Background	ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory(StAR) protein.
Categories	Primary Antibodies
Clonality	monoclonal
Description	ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single- stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site- specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.
Host	Mouse
Immunogen	lon peptidase 1, mitochondrial
Isotype	IgG2a
Molecular Weight	100 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PRSS15

Uniprot	P36776
Gene Id	9361
Clone No	9H10
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500-1:10000; IHC: 1:400-1:1600; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804813	FNab04821	100ug	$300		Add to Cart

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