Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Host
Rabbit
Immunogen
lin-9 homolog(C. elegans)
Isotype
IgG
Molecular Weight
62 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
BARA, TGS
Uniprot
Q5TKA1
Gene Id
286826
Research Area
Cell Division and Proliferation, Cancer, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)