LIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA(miRNA) biogenesis by specifically binding the precursor let-7(pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells; however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78% sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm, Nucleus
Clonality
polyclonal
Description
LIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells; however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78% sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B.
Host
Rabbit
Immunogen
lin-28 homolog B(C. elegans)
Isotype
IgG
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm, Nucleus
Synonyms
CSDD2, FLJ16517, lin 28 homolog B(C. elegans), Lin 28B, Lin28, LIN28B, Protein lin 28 homolog B
Antigen
Lin28B-specific
Uniprot
Q6ZN17
Research Area
Epigenetics, Stem Cells, Metabolism
Weight
28kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)