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Home / Primary Antibodies / Polyclonal Antibodies

LIMS1 antibody

SKU : BHA10804774

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Mfr.No.	FNab04782
Alternative Names	PINCH ; PINCH1
Background	The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.
Host	Rabbit
Immunogen	LIM and senescent cell antigen-like domains 1
Isotype	IgG
Molecular Weight	40 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PINCH, PINCH1

Uniprot	P48059
Gene Id	3987
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IHC, FC
Description	ELISA ; WB ; IF ; IHC ; FC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab04782.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804774	FNab04782	100ug	$240		Add to Cart

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