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Home / Primary Antibodies / Polyclonal Antibodies

LGR6 antibody

SKU : BHA10804758

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Mfr.No.	FNab04766
Background	Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Host	Rabbit
Immunogen	leucine-rich repeat-containing G protein-coupled receptor 6
Isotype	IgG
Molecular Weight	104 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	FLJ14471, GPCR, LGR6, VTS20631

Uniprot	Q9HBX8
Gene Id	59352
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB, FC
Description	ELISA ; IHC ; WB ; FC
Tested Application	WB: 1:200-1:1000; IHC: 1:20-1:200

Manual	FNab04766.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804758	FNab04766	100ug	$240		Add to Cart

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