Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides(LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria(PubMed:7517398, PubMed:24120359). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide(PubMed:7517398, PubMed:24120359).
Categories
Primary Antibodies
Clonality
monoclonal
Description
Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:7517398, PubMed:24120359). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359).
Host
Mouse
Immunogen
lipopolysaccharide binding protein
Isotype
IgG2a
Molecular Weight
53-60 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
LBP
Uniprot
P18428
Gene Id
3929
Clone No
2B8
Research Area
Cancer, Immunology, Metabolism
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)