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Home / Primary Antibodies / Polyclonal Antibodies

LARP1 antibody

SKU : BHA10804690

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Mfr.No.	FNab04698
Alternative Names	KIAA0731 ; LARP
Background	RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine(5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus(DENV)(PubMed:26735137).
Categories	Primary Antibodies
Clonality	polyclonal
Description	RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus (DENV) (PubMed:26735137).
Host	Rabbit
Immunogen	La ribonucleoprotein domain family, member 1
Isotype	IgG
Molecular Weight	140-150 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA0731, LARP

Uniprot	Q6PKG0
Gene Id	23367
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804690	FNab04698	100ug	$260		Add to Cart

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