Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9K23, and the hair keratins Ha1Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1K8, and the hair keratins, Hb1Hb6. As a type I keratin, keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. As a type I keratin, keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia.
Host
Rabbit
Immunogen
keratin 10
Isotype
IgG
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CK 10, CK10, Cytokeratin 10, K10, keratin 10, KPP, KRT10
Uniprot
P13645
Gene Id
3858
Research Area
Signal Transduction
Weight
59kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)