Plays an inhibitory role on natural killer(NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Host
Rabbit
Immunogen
killer cell lectin-like receptor subfamily G, member 1
Isotype
IgG
Molecular Weight
60 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
CLEC15A, MAFA, MAFAL
Uniprot
Q96E93
Gene Id
10219
Research Area
Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)