Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules (By similarity).
Host
Rabbit
Immunogen
kinesin family member 26B
Isotype
IgG
Molecular Weight
224-230 kDa or 17-22 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
KIF26B, kinesin family member 26B, Kinesin like protein KIF26B
Uniprot
Q2KJY2
Gene Id
55083
Research Area
Cell Division and Proliferation, Developmental biology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)