Mitotic kinesin required for chromosome passenger complex(CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate(GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Host
Rabbit
Immunogen
kinesin family member 20A
Isotype
IgG
Molecular Weight
100 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
MKLP2, RAB6KIFL
Uniprot
O95235
Gene Id
10112
Research Area
Cell Division and Proliferation, Developmental biology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)