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Home / Primary Antibodies / Polyclonal Antibodies

KDM2A antibody

SKU : BHA10804501

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Mfr.No.	FNab04509
Alternative Names	CXXC8 ; FBL7 ; FBXL11 ; JHDM1A ; KIAA1004
Background	Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono-and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Histone demethylase that specifically demethylates 'Lys- 36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys- 36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
Host	Rabbit
Immunogen	lysine(K)-specific demethylase 2A
Isotype	IgG
Molecular Weight	80-132 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004

Uniprot	Q9Y2K7
Gene Id	22992
Research Area	Epigenetics, Cancer, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804501	FNab04509	100ug	$280		Add to Cart

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