Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.
Host
Rabbit
Immunogen
kalirin, RhoGEF kinase
Isotype
IgG
Molecular Weight
200 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
DUET, DUO, HAPIP, TRAD
Antigen
KALRN
Uniprot
O60229
Gene Id
8997
Research Area
Developmental biology, Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)