Kallikrein-11, also called PRSS20 or TLSP, is a protein that in humans is encoded by the KLK11 gene. It is a member of the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. The gene contains 6 exons, the first of which is noncoding. KLK11 shares 48% amino acid sequence identity with mouse neuropsin, 43% identity with both human trypsin-1 and human kallikrein, and 38% identity with the mouse nerve growth factor gamma subunit. Alteate splicing of the KLK11 gene results in two transcript variants encoding two different isoforms which are differentially expressed. Weste blot analysis of recombinant KLK11 suggested that the protein is secreted and posttranslationally processed.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the C-terminus of human Kallikrein-11 (YTKVCKYVDWIQETMKNN) was used as the immunogen for this Kallikrein-11 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
Q9UBX7
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the Kallikrein-11 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.