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Home / Primary Antibodies / Polyclonal Antibodies

JNK antibody

SKU : BHA10804436

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Mfr.No.	FNab04444
Background	MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73, mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	mitogen-activated protein kinase 8
Isotype	IgG
Molecular Weight	46 kDa, 55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	c Jun N terminal kinase 1, JNK, JNK 46, JNK1, JNK1A2, JNK21B1/2, MAP kinase 8, MAPK 8, MAPK8, PRKM8, SAPK1

Uniprot	P45983
Gene Id	5599
Research Area	Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab04444.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804436	FNab04444	100ug	$260		Add to Cart

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