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Home / Primary Antibodies / Polyclonal Antibodies

ITM2C antibody

SKU : BHA10804410

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Mfr.No.	FNab04418
Alternative Names	BRI3
Background	Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C- terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Host	Rabbit
Immunogen	integral membrane protein 2C
Isotype	IgG
Molecular Weight	30 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	BRI3

Uniprot	Q9NQX7
Gene Id	81618
Research Area	Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804410	FNab04418	100ug	$280		Add to Cart

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